Polysubstance Use Disorder: Symptoms, Causes, Treatment, and More
Additionally, simultaneous administration of methamphetamine 2.0 mg/kg, intraperitoneal (ip) and nicotine (1.0 mg/kg ip) induces a conditioned place aversion in mice, while sequential administration of the same dose induces a CPP (Briggs et al., 2018). These data suggest that, unlike alcohol, early exposure to nicotine does not lead to increases in addiction-like behavior to cocaine […]
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